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Professor David Gottlieb trained in medicine at Sydney and Westmead Hospitals. He completed a doctorate in Medicine at the Royal Free Hospital in London before returning to Australia in 1990 to take up an academic position with the University of Sydney, where he is currently Professor of Haematology.

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He is Bone Marrow Transplant Program Director and Director of Cell Therapies at Westmead Hospital. His major research interest is in cellular immunotherapy for the treatment of infection and malignancy in immunocompromised patients especially in allogeneic stem cell transplant recipients and focuses on adoptive immunotherapy for rapid reconstruction of the immune system following intensive therapy. He has been principal investigator on multiple trials of pathogen-specific T cells and is a lead investigator on preclinical and clinical trials of CD19 CAR T cells currently being run at Westmead Hospital.

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He is past President of the Haematology Society of Australia and New Zealand and currently President of the Bone Marrow Transplant Society of Australia and New Zealand.