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Ze Cong has extensive work experience in the field of health economics and outcomes research. They began their career as a part-time Research Analyst at The Broad Foundation in 2005. In 2008, they joined Amgen and held various positions including Health Economics Manager, Health Economics Senior Manager, and Director of Global Health Economics. In 2018, Ze Cong joined Global Blood Therapeutics as the Senior Director of Health Economics and Outcomes Research. They then moved to GRAIL, Inc. in 2020 and held roles as the Director and later the Senior Director of Health Economics and Outcomes Research.

Ze Cong completed their Bachelor's degree in Physics from Tsinghua University from 1996 to 2000. They then pursued a Master of Science degree in Management from Tsinghua University from 2000 to 2003. Following this, Ze Cong attended Pardee RAND Graduate School from 2003 to 2008, where they obtained an MPhil and PhD in Health Economics and Health Policy.