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Dame was installed as 40th Master of Trinity College, Cambridge in 2019, following a distinguished global career as a clinical academic and public servant. Dame provided scientific leadership on both the local and global stage, including roles with the World Health Organisation, the United Nations and the UK government, where she was Chief Medical Officer (CMO) for England and Chief Medical Adviser to the UK government from March 2010 to September 2019. Specifically, Dame championed addressing Antimicrobial Resistance, making a difference to the health of humans, animals, agriculture and environment across the world. Her long-lasting influence also includes establishing both the National Institute of Health and Genomics England Ltd. She was named Dame Commander of the British Empire in 2009 and Dame Grand Cross of the Order of the Bath in 2020.