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Trained as a hematologist and an immunogeneticist, Claude has been a Principal Investigator at the Institute for Research in Immunology and Cancer (IRIC) of Université de Montréal since 2005 and is in charge of its immunobiology research laboratory.

He is a Professor in the Faculty of Medicine of the Université de Montréal and was a practicing clinician until 2018, at the Maisonneuve-Rosemont Hospital, where he created the histocompatibility laboratory and founded the bone marrow transplant unit.

Member of the Canadian Academy of Health Sciences, Claude has received the Acfas Léo-Pariseau prize (2011), the Michel-Sarrazin Award (2015) of the Club de recherches cliniques du Québec and the Bernhard Cinader Award of the Canadian Society for Immunology (2017).