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Lei Li has worked for five different companies since 2005. Lei began their career as a Research Fellow at the Institute for Molecular and Cell Biology (IMCB) in Singapore. In 2009, they moved to the Lilly Singapore Centre for Drug Discovery as a Principal Associate Scientist. In 2012, they joined the Faculty of Medicine at the National University of Singapore as a Senior Research Fellow. In 2019, they became an Operation Specialist - life cycle safety at IQVIA east asia. Most recently, in 2021, Lei Li was appointed as a Regional Clinical Affairs Manager at Endofotonics.

Lei Li received their PhD in molecular and cell biology from the National University of Singapore in 2005. Lei is currently enrolled in a Graduate Certificate program in Pharmaceutical Regulation at Duke NUS.