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Dr. Fleming hematological pathologist, who has been involved in iron metabolism research for >25 years. His research focuses on the area of iron and hematology. He has lead or has been involved in multiple discoveries in this domain, including the description of the transmembrane iron transporter DMT1/SLC11A2, the identification of the transferrin cycle endosomal ferrireductase STEAP3, the detection of mutations in TMPRSS6 in individuals with iron refractory iron deficiency anemia (IRIDA), as well as finding multiple genes responsible for novel forms of congenital sideroblastic anemia.