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Edd Fleming is a board member at CRISPR Therapeutics. Prior to joining CRISPR, Fleming was a pulmonary and critical care fellow at the University of California, San Francisco from June 1993 to December 1996. From July 1989 to June 1992, Fleming was a resident in internal medicine at Johns Hopkins Hospital. Fleming has also worked as a consultant at McKinsey and Company.

Edd Fleming attended Spartanburg Day School and Phillips Exeter Academy before studying chemistry at Harvard University. Edd then attended Vanderbilt University School of Medicine, where they earned their Doctor of Medicine (MD) degree.