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Brandy Appleby has a diverse work experience spanning several years. Brandy began their career in 2004 as an Executive Assistant at St. John Ambulance, where they worked until 2010. From 2010 to 2014, they served as an Administrator in the Specialties Unit at the Royal College of Physicians and Surgeons of Canada. Since 2014, Brandy has been working at CADTH, starting as a Project Coordinator and progressing to roles such as Project Coordinator Team Lead, Senior Project Coordinator, and currently Project Manager. Brandy'stime at CADTH is ongoing and they are responsible for managing projects.

Brandy Appleby completed Project Management Studies at Algonquin College of Applied Arts and Technology from 2017 to 2020. The focus of their education was in the field of Project Management.