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Nat worked in the private sector for 25 years as an entrepreneur starting two businesses, as management consultant at Bain and Company and venture capitalist at Accenture Technology Ventures. He remains an active investor in alternative assets.

Since 2002 Nat has been active in the social impact market. He is the co-founder of Impetus Trust, the first venture philanthropy trust fund in the UK. He is a founder trustee of the Education Endowment Foundation, the UK’s largest What Works Centre, chairing the Finance and Endowment Committee. He is the founder chair of Social and Sustainable Capital, one of the U.K.’s largest impact investment funds. He chairs Pause, a charity that works to support women to reduce the number of children taken into care. He was the chair of The National Lottery a community Fund in England until 2019.