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Guido R. Sigron has a long and varied work experience. Guido R. began their career in 2010 as Co-Founder of mydent AG. In 2012, they Co-Founded Zahnärzte am Reckholder AG. From 2015 to 2018, they held the role of Assistenzarzt Chirurgie at Spital Wil, followed by Assistenzarzt Mund-, Kiefer- und Gesichtschirurgie at Universitätsspital Basel (USB) and Kantonsspital Mönsterlingen. In 2019, they were Co-Founder of Bottmedical AG and Assistenzarzt Mund-, Kiefer- und Gesichtschirurgie at Landeskrankenhaus Feldkirch. Guido R. currently holds the role of Co-Founder at Bottneuro AG and Oberarzt Mund-, Kiefer- und Gesichtschirurgie at Kantonsspital Aarau AG.

Guido R. Sigron completed a Master of Medicine in Humanmedizin at the University of Zurich between 2011 and 2015. Prior to that, they obtained a Master of Dental Medicine in Zahnmedizin from the University of Zurich between 2002 and 2007.