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In addition to being a renowned expert in nanotechnology and a UCSD professor of Bioengineering and Nanoengineering, Dr. Heller has been successful in fostering four companies and hundreds of students. As a mentor for Biological Dynamics' CEO, Raj Krishnan, he was instrumental in bringing ACE technology from its original concept to what it is today.

Dr. Heller continues to push the cutting edge of medical diagnostics in multiple areas, the most significant of these being serum markers for TBI. He has over 50 issued US patents related to microelectronic chips, microarrays and integrated devices for DNA hybridization, miniaturized sample-to-answer diagnostic devices, biosensors, genomics, proteomics, nanotechnology and nanofabrication, nano-based DNA optical storage, and fluorescent energy transfer in DNA.