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Dr. Brown is an Associate Professor of Cancer Biology at the University of Pennsylvania and is an internationally recognized investigator in the field of DNA damage and repair. He is the author of many high-impact papers that have been published in top-tier journals such as Nature, Genes and Development, Cell Stem Cell, and Nature Genetics.

Dr. Brown’s research laboratory focuses on the importance of replication stress responses in preserving genome integrity and preventing cancer and aging. Dr. Brown is studying how the ATR pathway counters replicative stress, how replication stress relates to the process of aging, and whether suppression of the ATR pathway can serve as an effective cancer treatment.