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Geoff Higgins graduated in medicine from Edinburgh University in 2000. He undertook specialty training as a Clinical Oncologist at the Edinburgh Cancer Centre and became a Fellow of the Royal College of Radiologists in 2007. He subsequently moved to Oxford University and was awarded a D.Phil in 2010. For the last 9 years he has worked as a Clinician Scientist and Consultant Clinical Oncologist in Oxford. His laboratory research focuses on developing treatments that can selectively kill cancer cells when combined with radiotherapy. He previously demonstrated that disruption of POLQ induces tumour-specific radiosensitisation, and established the initial collaboration with Cancer Research Technology to develop inhibitors against this protein.

In the clinic, he has been the Chief Investigator of three clinical trials which have successfully translated new drug treatments into patient studies. Geoff also leads research relating to cancer imaging, and is joint-lead investigator of the CRUK funded National Cancer Imaging Translational Accelerator.