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Matthew Simmeth's work experience begins in 2017 as an Undergraduate Research Assistant at the University of Rhode Island. Matthew then worked as a Validation Engineering Intern at AllerQuest, LLC in 2018. In the same year, they also held the role of an Undergraduate Research Assistant at the University of Rhode Island. From 2019 to 2022, Matthew worked at the University of Illinois Chicago as a Graduate Research Assistant and later as a Teacher Assistant. In 2022, they joined AbbVie as a Chemist I and in 2023 they started working at Arranta Bio as a Senior Associate Scientist I.

Matthew Simmeth completed their Bachelor of Science (BS) degree in Chemical Engineering from the University of Rhode Island between the years 2015 and 2019. Following this, they pursued Graduate Studies in Biopharmaceutical Sciences at the University of Illinois Chicago from 2019 to 2022.