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Martin McMahon’s translational cancer research program focuses on the mechanisms underlying the initiation, progression and maintenance of metastatic melanoma, lung and pancreatic cancer. Martin graduated with a B.Sc. (Hons) in Biochemistry from Glasgow University in 1981 and a doctorate from King’s College, University of London in 1985. He completed a postdoctoral fellowship under the mentorship of J. Michael Bishop at the University of California, San Francisco (UCSF) investigating the mechanisms of action of oncoprotein kinases such as SRC, ERBB and RAF. In 1991, Martin established an independent research group at the DNAX Research Institute in Palo Alto working on the RAF family of protein kinases, now known to be mutationally activated in many human cancers. In 1998, Martin joined the faculty of the UCSF/Helen Diller Family Comprehensive Cancer Center where he served as the Efim Guzik Distinguished Professor of Cancer Biology, Co-Leader of the Experimental Therapeutics Program and Director for Professional Education. In 2015, he joined the faculty of the University of Utah where he currently serves as the Cumming-Presidential Chair of Cancer Biology in the Dept. of Dermatology, Senior Director for Preclinical Translation and Co-Leader of the Experimental Therapeutics Program in the Huntsman Cancer Institute.