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Sam Rogers has a diverse work experience in the non-profit sector, with a focus on development and leadership philanthropy. Currently, Sam holds the position of Director, Leadership Philanthropy at the American Association for Cancer Research since September 2022. Prior to this, Sam worked as the Vice President of Development at the Lung Cancer Research Foundation from January 2021 to September 2022, and as the Senior Director of Development from January 2019 to December 2020. Before joining the Lung Cancer Research Foundation, Sam held various roles at the Lymphoma Research Foundation, including Associate Director of Development from January 2018 to December 2018, Senior Manager of Development from July 2016 to December 2017, Donor and Community Relations Manager from June 2015 to June 2016, and Program and Communications Coordinator from November 2010 to June 2015. Sam began their career at the Alliance for Lupus Research as a Media and Communications Coordinator from an unknown start date to 2010.

Sam Rogers obtained a Bachelor's degree in Urban Studies/Affairs from The New School in 2004. Later, from 2013 to 2016, they pursued a Masters of Science degree in Urban Policy Analysis & Management at the same institution. Prior to attending college, Sam Rogers attended Newton South High School, though no degree or field of study is mentioned for this period. In addition to their educational qualifications, Sam Rogers holds a certification as a Certified Fund Raising Executive from CFRE International, although the month and year of its attainment are not provided.