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Isaac Wolff has a diverse work experience spanning various fields. Isaac started their career at FSP Sports Ltd as a Director from 2004 to 2009. Isaac then worked as a Special Constable at the Metropolitan Police from 2010 to 2012. In 2016, they worked as a Doctor at Lister Hospital and later as a Surgical Trainee in Cardiothoracic Surgery at Royal Papworth Hospital NHS Foundation Trust in 2017. From 2018 to 2022, Isaac was a Senior Clinical Fellow at the Royal Brompton & Harefield Hospitals Specialist Care. Isaac also served as the Chairman of the Junior Doctor Forum and Medical Education Committees RBHT from 2019 to 2020. Isaac joined Allergan in 2022 as a Senior Manager in Clinical Development before becoming an Associate Director of Clinical Development Devices in Allergan Aesthetics in 2023. Isaac is involved in leading clinical trials and developing new devices, treatments, and interventions for aesthetic indications.

Isaac Wolff earned a Bachelor of Medicine, Bachelor of Surgery (MBBS) degree in Medicine from St George's, University of London from 2012 to 2016. Prior to that, they completed a Bachelor of Science (BS) degree in Biomedical Sciences, General and Biomedicine from Birkbeck, University of London from 2008 to 2012.