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Yi Han has a diverse work experience in the pharmaceutical industry. Starting in 2009 at Jiangsu Hengrui Medicine Co., Ltd, they worked as a Project Manager. They then moved on to Novartis in 2010, where they initially worked as a Scientist and later as an Investigator in Clinical PKPD. In 2015, they joined AstraZeneca as a Clinical Pharmacology Manager. In 2016, they joined Pfizer as a Sr Portfolio and Project Manager, and later became the Head of Portfolio and Project Management for Development China. From 2019 to 2020, they worked at EverInsight Medicines as the Head of Portfolio and Program Management. In 2020, they joined AffaMed Therapeutics as the VP and Head of Strategy & Portfolio Management, and in 2021, they moved to AffaMed Technologies as the General Manager.

Yi Han holds a Bachelor's degree in Pharmacy (Japanese) from Shenyang Pharmaceutical University, which was obtained from 1997 to 2002. Afterwards, from 2002 to 2007, Yi Han pursued a PhD in Pharmacy at the National University of Singapore. Following the PhD, from 2008 to 2009, Yi Han completed a postdoctoral program in the Department of Clinical Pharmacology at the University of Helsinki. More recently, Yi Han obtained a PMP (Project Management Professional) certification from PMI in 2017.