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Andrew Powell is an independent consultant who has served as a member of Aclaris’ board of directors since January 2017. Mr. Powell served as Senior Vice President, General Counsel, and Corporate Secretary of Medivation, Inc. from 2015 through the company’s acquisition by Pfizer, Inc. in 2016. Prior to Medivation, Mr. Powell served as Executive Vice President, General Counsel and Corporate Secretary of InterMune, Inc. from 2013 to 2015, where he helped the company prepare for the U.S. approval and launch of Esbriet® (pirfenidone) as a treatment for idiopathic pulmonary fibrosis and played a leadership role in InterMune’s acquisition by Swiss drugmaker Roche Holdings AG. Immediately prior to joining InterMune, he was Executive Vice President, General Counsel, and Secretary at Cornerstone Therapeutics, Inc. through its successful sale to Chiesi Farmaceutici S.p.A. Prior to Cornerstone, Mr. Powell served as Senior Vice President and General Counsel at ImClone Systems, Inc. where he helped the company grow before playing a key role in a successful process that resulted in a sale to Eli Lilly and Company. Prior to ImClone Systems, he was part of the senior team that repositioned CollaGenex Pharmaceuticals, Inc. as a leader in dermatology. Early in his career, Mr. Powell held positions of increasing responsibility for nearly 15 years at the multinational health care company Baxter International, Inc., where he was instrumental in a series of transactions that established Baxter throughout Asia. He currently serves on the board of directors of the publicly held company Landec Corporation, a health and wellness solutions company, and Silverback Therapeutics, Inc., a biopharmaceutical company, as well as a member of the boards of directors of various privately held companies in the life sciences industry. Within the past five years, he served on the boards of directors of Synthorx Inc., a biopharmaceutical company acquired by Sanofi Aventis in January 2020, and Motif Bio plc. Mr. Powell received a Bachelor of Arts from the University of North Carolina at Chapel Hill and a Juris Doctorate from Stanford Law School.